What is i-PRF?

i-PRF (Platelet-Rich Fibrin) treatment is a cutting-edge advancement following PRP (Platelet-Rich Plasma) therapy. 

While similar to PRP, PRF stands out because it doesn’t use anticoagulants or chemicals, making it more effective. PRF contains up to 10x more platelets and releases growth hormones gradually over time. This thick, gel-like substance continues to stimulate hair follicles and promote hair growth long after treatment, unlike PRP which releases hormones more quickly. 

PRF is a non-surgical, minimally invasive procedure that not only stimulates hair growth but also improves hair density and strength. It’s a promising solution for anyone experiencing hair thinning or loss, regardless of gender.

How Does PRF Work for Hair Loss?

The PRF treatment process begins similarly to PRP. A small amount of blood is drawn from the patient and then undergoes specialized centrifugation. This process separates the platelets and growth factors from other blood components, resulting in a PRF solution rich in essential bioactive proteins for hair growth and reducing hair fallout.

The key difference between PRF and PRP is the absence of chemicals and anticoagulants in PRF. This allows the plasma to form a fibrin scaffold rich in platelets and white blood cells when introduced into the scalp. This fibrin clot enhances cell adhesion and gradually releases growth factors over an extended period, making PRF more effective than PRP.

Experience the innovative PRF treatment for long-lasting, natural hair regrowth and improved hair density.

What Growth Factors are in i-PRF?

The PRF substance is packed full of growth factors, which are essential proteins that play a crucial role in the body’s healing processes. The growth factors in PRF include:

Basic Fibroblast Growth Factor (bFGF):

Known for stimulating cell growth, bFGF plays a significant role in tissue regeneration and wound healing. It supports the growth of new blood vessels and aids in the repair of damaged tissues.

Platelet-Derived Growth Factor-BB (PDGF-BB):

This growth factor is important for cell division, promoting the growth of connective tissues, blood vessels, and cell migration to the treatment site, significantly contributing to tissue repair.

Transforming Growth Factor β-1 (TGF-β1):

TGF-β1 is instrumental in regulating cell growth, production, and differentiation. It helps in the formation of new blood vessels and collagen, and is crucial for wound healing and tissue remodelling.

Insulin-like Growth Factor-1 (IGF-1):

Vital for cell growth and development, IGF-1 stimulates the production and differentiation of various cell types. It aids in tissue repair and regeneration.

Vascular Endothelial Growth Factor (VEGF):

VEGF also stimulates the formation of new blood vessels, improving blood supply to the treated area and supporting tissue healing.

How Does a PRF Facial Work?

i-PRF facial shares a starting point with our PRP Facial. A small blood sample is taken from the patient – giving reason for the name “Vampire Facial” – which then undergoes a specialised centrifugation process. By separating the platelets and growth factors from other components in the blood, the centrifuge creates a PRF solution that is highly rich in platelets and bioactive proteins essential for regenerating and revitalising the skin.  

Similar to our PRF Hair Loss Treatment, our PRF treatment for face goes a step above PRP, as it does not involve the use of any anticoagulants or chemicals and uses up to 10x more platelets.  

The absence of chemicals in PRF treatments means that the plasma is allowed to form a fibrin scaffold that is rich in platelets and white blood cells when introduced to the treatment area. This causes the gradual release of growth factors over time which help to sustain the results for longer, as opposed to PRP’s quicker release, which offers shorter term effects.   

Benefits of i-PRF Therapy for Face

  • Natural Rejuvenation

PRF facial treatments at promote natural skin rejuvenation without the use of any anticoagulants or chemical, harnessing the body’s own platelets and growth factors to stimulate collagen production for enhanced skin vitality and radiance.

  • Long-Lasting Results

A slower and more sustained release of growth factors in PRF contributes creates much longer-lasting results compared to PRP, providing a continuous stimulation of collagen production for a lasting impact.

  • Enhanced Cell Adhesion

The absence of chemicals allows the PRF plasma to form a platelet and white blood cell-rich fibrin scaffold, enhancing cell adhesion and optimising the effectiveness of the treatment.

  • Minimal Downtime

Our PRF facial treatment is known for its minimal downtime, meaning you can get back to your daily activities as soon as possible.

PRF Treatment Frequently Asked Questions

PRF Treatment involves using the patient’s own blood to create a more advanced concentration of platelets and growth factors compared to PRP. PRF’s thicker consistency allows for a more sustained release of these healing elements.

How does PRF Treatment work, and what are its applications in various medical and aesthetic procedures?

PRF Treatment works by collecting and concentrating platelets, fibrin, and white blood cells from the patient’s blood. It is used in a variety of applications, including skin rejuvenation, hair restoration, and orthopedic procedures.



What makes i-PRF unique in terms of its consistency and release of growth factors?

PRF is unique due to its fibrin matrix, which gives it a gel-like consistency. This allows for a slower and more sustained release of growth factors, promoting longer-lasting therapeutic effects compared to traditional PRP.


Who is an ideal candidate for PRF Treatment, and how is eligibility determined?

Ideal candidates for PRF Treatment include individuals seeking skin rejuvenation, hair restoration, or orthopedic healing. Eligibility is often determined during a consultation and depends on individual health and treatment goals.

Can PRF Treatment be combined with other aesthetic or medical procedures for enhanced results?

Yes, PRF Treatment is often used in combination with other procedures, such as dermal fillers or surgical interventions, to enhance healing and promote better outcomes in both aesthetic and medical applications.



How many sessions of PRF Treatment are typically recommended to see optimal results?

The number of PRF sessions varies depending on the specific treatment goals and the individual’s response. In some cases, a series of sessions may be recommended for optimal results.



Is PRF Treatment painful, and is there any downtime associated with the procedure?

PRF Treatment is generally well-tolerated, and any discomfort is minimal. There may be mild swelling or bruising at the injection or treatment site, but downtime is typically short, allowing for a quick return to normal activities.

What is the expected timeline to see results after PRF Treatment for different applications?

Results from i-PRF Treatment can vary. For skin rejuvenation, improvements may be noticed within a few weeks, while hair restoration results may become apparent over a few months. Orthopedic healing timelines depend on the specific condition being treated.



Are there any potential side effects or risks associated with PRF Treatment?

i-PRF Treatment is generally considered safe, as it utilizes the patient’s own blood. Side effects are minimal and may include temporary swelling or bruising at the treatment site. Any specific concerns or conditions should be discussed during the consultation

Can PRF Treatment address specific orthopedic conditions, and what types of injuries can it assist in healing?

i-PRF Treatment is often used in orthopedics to aid in the healing of various injuries, including tendonitis, ligament injuries, and osteoarthritis. It promotes natural healing and tissue regeneration in these areas.

Difference between PRP and i-PRF:

Platelet-rich plasma

The platelet-rich plasma (PRP) consists of a high concentration of autologous platelets in a small amount of plasma following centrifugation of blood from the patient. These platelets present in the PRP release numerous substances that promote tissue repair and affect the behaviour of other cells.

Platelet-rich fibrin

Platelet-rich fibrin (PRF) is a more advanced platelet concentration and it is achieved with no biochemical manipulation of blood. This technique does not use anticoagulant. This feature makes the product easily usable, with a low rate of mistakes during the preparation stage. The fibrinogen is initially concentrated in the upper part of the tube but, upon the contact with thrombin, normally present in the blood, it is converted into fibrin. The platelets are retained within this fibrin, this is thought to release a higher amount of growth factors over a longer time period.

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